Enhanced Tumor Delivery of Gemcitabine via PEG-DSPE/TPGS Mixed Micelles
نویسندگان
چکیده
منابع مشابه
Enhanced Tumor Delivery of Gemcitabine via PEG-DSPE/TPGS Mixed Micelles
Gemcitabine is a potent anticancer drug approved for the treatment of pancreatic, non-small-cell lung, breast, and ovarian cancers. The major deficiencies of current gemcitabine therapy, however, are its rapid metabolic inactivation and narrow therapeutic window. Herein, we employed polyethylene glycol-b-distearoylphosphatidylethanolamine (PEG-DSPE)/tocopheryl polyethylene glycol 1000 succinate...
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ژورنال
عنوان ژورنال: Molecular Pharmaceutics
سال: 2014
ISSN: 1543-8384,1543-8392
DOI: 10.1021/mp4005904